Hypereosinophilic syndrome represents a heterogenous group of disorders with the common features of idiopathic prolonged eosinophilia of undetectable cause and organ system dysfunction.
We experienced a case of hypereosinophilic syndrome in a 58 year old man who has been suffered from fever, chilling, generalized exfoliative dermatitis, periorbital angioedema and oral ulcer for 3 weeks duration. The blood eosinophil count was
7436/㎣and skin, liver, bone marrow biopsy revealed marked infiltration of eosinophils. We treated him with corticosteroid, but 5 months later, he died due to hepatoencephalopathy, hepatorenal syndrome, disseminated intravascular coagulopathy and
acute
respiratory distress syndrome. (Kor J Dermatol 1994 ; 32(3) : 503~508)
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